Steroid responsive disc neovascularisation in uveitis associated with juvenile chronic arthritis

Methotrexate and chronic uveitis associated with juvenile idiopathic arthritis.

Neovascularisation associated with posterior uveitis.

Twenty-six patients (39 eyes) with retinal neovascularisation associated with ocular inflammation were identified from the retinal vasculitis clinic at St Thomas's Hospital. Eight patients had sarcoidosis, seven patients Behçet's disease, and 11 had idiopathic retinal vasculitis. Twenty-three patients had required systemic therapy to control the inflammation and 11 patients received laser photo...

Juvenile idiopathic arthritis-associated uveitis

Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease of childhood, with JIA-associated uveitis its most common extra-articular manifestation. JIA-associated uveitis is a potentially sight-threatening condition and thus carries a considerable risk of morbidity. The aetiology of the condition is autoimmune in nature with the predominant involvement of CD4(+) T cells. However, ...

Juvenile Idiopathic Arthritis associated uveitis

Systemic JIA represents 20% of all JIA cases. It is characterized by the onset of high-grade fever associated with multiple extra-articular manifestations. [2] These include maculopapular rash, generalized lymphadenopathy, hepatomegaly, splenomegaly, pericarditis, and pleuritis. Joint involvement is initially mild or absent, but becomes the more prominent feature of the disease as the patient a...

Adalimumab in juvenile idiopathic arthritis-associated chronic anterior uveitis.

OBJECTIVE To evaluate the efficacy of adalimumab in juvenile idiopathic arthritis (JIA)-associated uveitis. METHODS Retrospective observational study of 20 patients with JIA and chronic uveitis on adalimumab treatment. The ocular inflammation and improvement was assessed according to the Standardization of Uveitis Nomenclature criteria. RESULTS At the initiation of adalimumab, the mean age ...